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Innovative biomarker technologies address limitations in traditional systems, such as low sensitivity, poor reproducibility, and complex protocols. Rod-shaped magnetic particles (RSMPs) and encoded viral micropatches have emerged as transformative solutions. RSMPs enable automation in immunoassays, offering precision and eliminating human errors. These systems facilitate multiplex diagnostics with low limits of detection (LOD), rivaling molecular techniques like PCR, and allow rapid testing for diseases such as Influenza and COVID-19. Encoded viral micropatches enhance gene delivery and multiplexed cellular assays, reducing cross-contamination through localized delivery and shape-coded designs. Their compatibility with high-content imaging systems advances drug discovery and cellular research. Together, these technologies improve the efficiency and scalability of diagnostics while supporting diverse applications in clinical and research settings. By overcoming the drawbacks of conventional biomarkers, these advancements enable rapid, precise, and cost-effective solutions, driving progress in the fields of diagnostics and biomedicine.
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Song, S. H., Lim, S., Choi, H. Y., Kim, J. H., Jung, Y. G., & Park, W. (2020). New precision engineering methods for low‐cost mass production of functional giant magnetic glass‐coated particles as immune biomarkers. Advanced Engineering Materials, 22(6), 2000060.
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